Cancer Epigenetics

Adult cancer cells isolated from clinical tissue biopsies have been discovered to have both global DNA epigenetic changes and gene-specific hypermethylation. The genomes of people with colorectal cancer were shown to be hypomethylated in early investigations on cancer epigenetics. Silent sections of the genome and areas of the genome that are typically hypermethylated were discovered to be demethylated in these patients. However, hypermethylation of CpG islands has been associated with aberrant gene activation in some cancers, such as the suppression of tumor-suppressor genes. Repeating DNA sequences, such as microsatellites, become functionally aberrant and promote cancer when DNA is hypermethylated. Abnormal epigenetic modulations in the MLH1 promoter lead to the distortion of microsatellites in colorectal and ovarian malignancies.

  • Posttranslational histones
  • Noncoding RNAs
  • Micro-RNAs

Related Conference of Cancer Epigenetics

August 23-24, 2023

5th World Congress on Complementary & Alternative Medicine

Prague, Czech Republic
September 11-12, 2023

9th World Congress on Internal Medicine and Primary Care

Toronto, Canada
September 25-26, 2023

6th World summit in Alternative Proteins

Las Vegas, USA

Cancer Epigenetics Conference Speakers

    Recommended Sessions

    Related Journals

    Are you interested in