Epigenetics and Human DiseasesConference

Autoimmune Diseases

Subconscious is essential for the immune system to operate normally, and a lack of it can lead to autoimmune diseases. Studies on autoimmune diseases in monozygotic and dizygotic twins have revealed that epigenetic changes may play a role. Failure of epigenetic homeostasis in response to environmental factors can modify the expression of particular differentiated cells' genes, which can lead to dysregulated self-tolerance. The immune system and target organ are the two primary players in an autoimmune disease process. Epigenetically regulated immune cell functions include hematopoietic lineage, antigen-receptor rearrangement, allelic exclusion, and inducible immune responses to infections. Autoimmunity illness may be exacerbated by changes to epigenetic processes governing immunological development.