6^th International Conference on Epigenetics and Human DiseasesConference June 08-09, 2023 Valencia, Spain

TRACK 1: Epigenetic Therapy

The administration of using medications or other methods that have an impact on the epigenome to treat medical complications is referred to as epigenetic hospital treatment. Epigenetic pathways have an impact on a number of diseases, such as diabetes, cancer, cardiopathy, and mental problems. Epigenetic medical intervention may be another direct way to change such circuits. Epigenetic therapy may both eliminate cancer cells that have evolved in response to treatments and stop the spread of malignant cells at their root. On the other hand, because some epigenetic effects may be reversible, many scientists have turned their attention to epigenetic medical support. Epigenetic pathways play a role in the development of numerous diseases, such as cancer, cardiopathy, diabetes, and mental depression. Epigenetic therapeutic procedure may be another method for causing such circuits to fire.

• DNA methylation
• Modifications to chromatin structure
• Loss of imprinting

TRACK 2: Nutrigenomics

Nutrigenomics involves the characterisation of sequence product, their physiological perform and their interactions. It focuses on the impact of nutrients on ordination, proteome, metabolome and explains the link between these specific nutrients and nutrient-regimes on human health. Nutrigenomics as a search field greatly depends on the recent development of advanced technologies that enable USA to method an outsized quantity of knowledge concerning sequence variants. These supposed ‘-omic’ technologies: genomic, proteomic, metabolomics and transcriptomic, enable USA to spot and live many various varieties of molecule at the same time. This is often vital only if most chronic diseases aren't caused by inheritable mutations or single sequencetic effects littered with one dietary exposure and however advanced interactions among an awfully sizable amount of various gene variants

• Genomics
• Proteomics
• Metabolomics
• Transcriptomics

TRACK 3: Cytogenetics

The subject of the polymer structure inside the cell organ is covered by the branch of genetics known as genetics. In contrast to cell division and chromosome type, this polymer is condensed. The cytology refers to the number and shape of chromosomes, the precise positioning of genes on chromosomes, and anomalies in bodily behaviour and biological processes. Diabetes and mental illnesses are regulated by epigenetic pathways in a manner that is continuously constant thanks to the shape of chromosomes in an exceptionally cell of a chosen species. Utilizing epigenetic therapy as a form of treatment is another technique to trigger such circuits.

• Carrier testing
• Pharmacogenetics
• Prenatal testing
• New-born screening

TRACK 4: DNA Methylation

DNA methyl reticulation may be a process that involves the addition of methyl teams to the polymer molecule. While not poignant the sequence, methylation will modify the activity of a polymer region. Once polymer methylation happens at a sequence promoter, it always suppresses sequence transcription. In mammals, polymer methylation is crucial for traditional development and is related to variety of key processes as well as genomic acquisition, X-chromosome inactivation, repression of permutable components, aging and carcinogenesis. Aging, environmental effects and way variables like smoking and food all because organic chemistry changes within the polymer over time. These oftentimes end in polymer methylation, which is that, the addition of methyl radical teams to specific polymer sequences while not poignant the polymer structure.

• Bisulfite sequencing
• Adenine
• Cytosine.

TRACK 5: Epigenetic of Diabetes

Epigenetic retraining of internal secretory target organs, islet cells, and immune cells power-assists the development of kind two polygenic disorders, but sex cell reprogramming has transgenerational repercussions. Epigenetic changes brought about by the symptom are present in tissues affected by diabetes complications.

• Fatty acids
•  Human Sperm

TRACK 6: Depression and Mental illness

Sometimes physical problems can cause depression. But totally different times, symptoms of depression are a vicinity of an extra advanced drugs draw back. a private with major depression, or major depression, feels a profound and constant sense of despair. Major depression is marked by a mixture of symptoms that interfere with the person's ability to work, study, sleep, eat, and luxuriate in once gratifying activities. Major depression might occur only one occasion but extra sometimes happens again and again in an exceedingly very period of time. Exercise is incredibly helpful for the depressed mind. It permits you to higher handle stress, and thus the endorphins discharged throughout exercise give you a mental boost. Whereas science has but to go looking out a cure for mental disorders like depression, it's entirely come-at-able to live a self-satisfied and fulfilling life in spite of it.

• Seasonal affective Disorder
• Psychotic Depression
• Loneliness
• Alcohol and drugs

TRACK 7: Neurodegenerative Diseases

Intractable illnesses known as neurodegenerative diseases cause the progressive degeneration or death of nerve cells. This results in developmental or mental functioning issues (ataxias) (called dementias). It's a catch-all phrase for a wide range of ailments that mostly affect the neurons in the human brain tissue. With age, there is a significant increase in the risk of developing a neurodegenerative condition. In addition to an older American population, increased global prosperity has raised the possibility that many more people would be affected by neurodegenerative diseases in the decades to come. It's possible that Sandhoff disease is a rare genetic condition that gradually damages nerve cells (neurons) in the brain and neural structure.

• Sandhoff Virus
• Alzheimer's illness
• Disease of Huntington's

TRACK 8: Cardiovascular Diseases

Heart and blood vessel disorders are often referred to as cardiovascular disease. Damage to the arteries in several organs, including the kidneys, eyes, heart, and brain, can also be linked to it. A blockage that prevents blood from flowing to the heart or brain is the principal cause of heart attacks and strokes, which are typically sudden, acute events. The inner walls of the blood vessels that supply the heart or brain have a build-up of fatty deposits, which is the most frequent cause of this. About 60 to 100 times each minute, it beats with a steady, consistent pace. This occurs roughly 100,000 times daily. Your heart can occasionally become out of rhythm. Arrhythmia is the medical term for an abnormal or erratic heartbeat..

• Heart Valve Disease
• Alzheimer's Disease
• Arterial Disease
• Heart Rheumatoid Arthritis

TRACK 9: Gynaecological and Obstetrical Diseases

A medical expert in obstetrics concentrates on OB, which covers all facets of pregnancy, from prenatal treatment through postpartum care. Unlike gynaecologists, associate medical specialists do not deliver babies. A medical specialist can also recommend treatments to help you conceive, such as fertility medications. Obstetrics and medicine, often known as OB and medical speciality, is a branch of medicine that includes the two subspecialties of OB (covering pregnancy, childbirth, and the postpartum period) and medical specialty (covering the health of the female genital system, uterus, and fallopian tubes)

• Missing periods
• Irregular intervals
• Heavy phases
• Family preparation

TRACK 10: Epigenetics Biomarkers

In order to identify patients with hazardous tumours at the earliest possible stage, establish an accurate prognosis, and forecast and track the effectiveness of particular therapy, biomarkers are playing a crucial role and posing a high risk to people who are being screened for cancer. the treatment of cancer The stability, frequency, and noninvasive accessibility of epigenetic modifications in body fluids make them novel biomarkers. Epigenetic alterations can be important therapeutic targets because they can be reversed.

• Biomarkers for cancer
• Genetic biomarkers

TRACK 11: Molecular Diagnostics of Human Diseases

The analysis of high-dimensional and multimodal biomedical data has been suggested by a few machine learning advancements, which have improved the discovery, detection, and remedial checking of early infection movement. With advances in clinical epigenetics that distinguish Sirtuin 1 as deficient and to be associated with lethal invulnerable responses crucial to mitophagy, diagnostic testing and plasma analyte examination cannot determine atomic mitochondria deficiencies. To determine the significance of symptomatic clinical biochemistry tests, sirtuin analysis in plasma and body fluids is essential. This will enable the early diagnosis of diseases such as cardiovascular diseases, non-alcoholic fatty liver infection, metabolic diseases, and neurodegenerative diseases. Doctors are concerned about the under diagnosis of numerous chronic diseases that are linked to diabetes and organ disorders around the world and the speed at which modified cell death is increasing.

• Bioinformatics
• Microarray

TRACK 12: Autoimmune Diseases

Subconscious is essential for the immune system to operate normally, and a lack of it can lead to autoimmune diseases. Studies on autoimmune diseases in monozygotic and dizygotic twins have revealed that epigenetic changes may play a role. Failure of epigenetic homeostasis in response to environmental factors can modify the expression of particular differentiated cells' genes, which can lead to dysregulated self-tolerance. The immune system and target organ are the two primary players in an autoimmune disease process. Epigenetically regulated immune cell functions include hematopoietic lineage, antigen-receptor rearrangement, allelic exclusion, and inducible immune responses to infections. Autoimmunity illness may be exacerbated by changes to epigenetic processes governing immunological development.

• Graves illness
• Autoimmune thyroiditis
• Number of sclerosis
• Grave myasthenia

TRACK 13: Cancer Epigenetics

Adult cancer cells isolated from clinical tissue biopsies have been discovered to have both global DNA epigenetic changes and gene-specific hypermethylation. The genomes of people with colorectal cancer were shown to be hypomethylated in early investigations on cancer epigenetics. Silent sections of the genome and areas of the genome that are typically hypermethylated were discovered to be demethylated in these patients. However, hypermethylation of CpG islands has been associated with aberrant gene activation in some cancers, such as the suppression of tumor-suppressor genes. Repeating DNA sequences, such as microsatellites, become functionally aberrant and promote cancer when DNA is hypermethylated. Abnormal epigenetic modulations in the MLH1 promoter lead to the distortion of microsatellites in colorectal and ovarian malignancies.

• Posttranslational histones
• Noncoding RNAs
• Micro-RNAs

TRACK 14: Epigenetic and Environment

At any one time, the epigenome is home to every epigenetic alteration, including polymer methylation, straightforward protein modifications, non-coding RNAs, and others. Since the epigenome of a cell is dynamic, environmental and genetic variables will have an impact. Additionally, because epigenetic modifications are reversible, the ordination is adaptable to environmental changes. We are exposed to a variety of environmental toxins on a regular basis, which could modify our epigenome and affect our health. It is undeniably true that the toxins produced by L. monocytogenes, Eubacterium, and Strep respiratory disease significantly change the acetylation of simple proteins.

• Methylation
• Histone modification

TRACK 15: Chronic Diseases

Age generally causes chronic diseases to become more frequent. Joint inflammation, cardiovascular disorders including heart attacks and stroke, cancers like breast and colon disease, diabetes, epilepsy and seizures, obesity, and oral health problems are among the most common chronic infections in developed countries. In the United States, chronic diseases account for 70% of all causes of mortality and disability, according to the Center for Disease Control. Aside from that, recurring problems like back pain and anguish are typically the main causes of decreased profitability and rising healthcare costs. According to data from the World Health Organization, even in regions where infectious diseases are prevalent, chronic disease is the leading cause of premature mortality globally.

• Diabetes
• Chronic Back Pain
• Depression
• Cardiovascular Diseases

TRACK 16: Plant Epigenetics

Seedlings are masters of epigenetic control. We can demonstrate that eukaryotes are the home of the majority of the main epigenetic mechanisms. DNA methylation takes place in plant genomes because of CG, CHG, and CHH sequence contexts, and the patterns that result from this reflect equilibrium between the activities of the enzymes that instal, maintain, and remove methylation. Similar to other eukaryotes, plants also include histone-modifying enzymes that affect epigenetic states. These enzymes are encoded by fairly vast gene families, allowing for both overlapping and diverse roles. To fight viruses, control transposons, direct development, and assist with genome organisation, RNA-mediated gene silencing is performed utilising a number of unique methods. Because of the interaction between DNA methylation, histone modification, and noncoding RNAs, plants have a multi-layered and robust epigenetic circuitry.

• Crop epigenetics
• DNA Coding 
• Mitochondrial DNA

TRACK17: Epigenetics and Metabolism in Health and Disease

Oncology formation and progression caused by epigenome changes and metabolism is facilitated by the molecular rewiring of cancer cells. Simple protein and polymer modification enzymes are modified as a result of metabolic reprogramming caused by oncogenes and expression of metabolism-associated genesis, which is in turn controlled by epigenetics. This promotes the well-known metabolic cancer cells reprogramming and, as a result, sterilises the molecular basis.

• Epigenetics in reproductive health
• Human illness prevention
• Neurological system

TRACK 18: Chromatin and Chromosome Dynamics

The parent cell is either entirely or partially contained in the DNA molecule known as a chromosome. The condensation of chromatin is employed to create the chromosome. Chromatin structure is impacted by a number of things. The general structure depends on the Cell Cycle stage. Responses to external stimuli and cell-type-specific developmental programmes determine the arrangement of the many protein-coding expression patterns genes.

• Chromosomal abnormalities
• Autosomal chromosomes
• Homo- and heterochromosomes

TRACK 19: Histone Modifications

Acetylation, methylation, ubiquitination, citrullination, and phosphorylation of particular amino acids within the histone protein are just a few examples of the many different forms of histone modifications. These changes are typically made near the C-terminal (or "tail") end of the protein. Changing the overall chromatin structure and/or influencing the binding of transcription effector molecules are two ways that histone modifications affect gene expression. The effect of histone methylation on gene expression is highly context-dependent because it can either promote or repress gene expression. The background of methylation of histones H3 and H4 provides the best characterization of the biological role of histone methylation.

• Nucleosomes
• chromatin

TRACK 20: Rare Diseases

Although market players were not interested in utilising rare disorders to produce medicines, they became known as orphan diseases. Financial incentives were established under the Orphan Drug Act to entice businesses to provide novel medications for rare diseases. The rare disease community has been using this estimate for a number of decades to demonstrate that while specific diseases may be uncommon, there are a lot of people who have rare diseases overall. More than 6000 uncommon diseases are characterised by a wide range of abnormalities and symptoms that differ not only from one disease to another but also from one patient to another who is suffering from the same condition. Symptoms that are somewhat common can mask rare diseases, causing misdiagnosis and delaying treatment.

• Angelman Syndrome
• Gaucher's Disease
• Fabry Disease
• Acrogeria

The 6th International Conference on Epigenetics and Human Diseases welcome presenters, exhibitors, and attendees from everywhere the world to Valencia, Spain throughout June 08-09, 2023. The organizing committee is getting ready for AN appealing and informative conference program as well as lectures, workshops, symposia on a good class of topics, poster displays, young scientist forums, and numerous programs for participants from across the world. In addition, a growing sedentary lifestyle, increasing incidence of diabetes and chronic diseases globally has contributed to the growth rate of the Human Microbiome market. We tend to gracefully invite you to unite North American country at the Epigenetics and Human Diseases, wherever you'll have AN intelligible expertise with students from overseas. The Organizing Committee and every attendee of HUMAN DISEASES 2023 are trying to fulfill your expectations in Valencia, Spain.

Cell Viability Assays and Consumables:

With a compound yearly growth rate (CAGR) of 8.3% from 2018 to 2023, the global market for cell viability assays is expected to increase from $2.7 billion in 2018 to $4.1 billion in 2023.

This report's scope is comprehensive and includes prospective application areas in a variety of industries as well as the many product kinds that are offered on the cell viability tests market. Instruments and consumables are the two product categories that make up the cell viability tests market. With anticipated values generated from manufacturer revenues, revenue predictions are provided for each product, application, cell type, and end user from 2018 to 2023.

Global Markets for Vaccine Technologies:

The worldwide economy for vaccination technologies is anticipated to increase at a compound annual growth rate (CAGR) of 7.6% from 2021 to 2026, from $38.2 billion to $55.1billion.

Critical trends in the vaccination market are explained in this research. Insights are given to stakeholders and potential competitors by discussing the market determinants that serve as motivating or restricting forces.Animal vaccinations are not included in this report; it solely covers human vaccines.

This study focuses at spending on research and development (R&D), rising rivalry, and new technologies that are shaping the market. Future market expansion is impacted by these developments, new product introductions, and evolving lifestyles. This paper also discusses company merger, acquisition, and partnership strategies.

Epigenetic & Human diseases Related Societies:

Europe Societies:

• Clinical Epigenetics Society 
• The Epigenetics Society
• Association of Clinical Cytogeneticists
• British Society for Human Genetics
• Clinical Genetics Society
• Clinical Molecular Genetics Society
• Genetics Society
• Human Genetics Commission
• Austrian Society for Human Genetics
• Belgian Society for Human Genetics
• Czech Society of Medical Genetics
• Danish Society of Medical Genetics
• Dutch Association of Clinical Genetics
• Finnish Society of Medical Genetics
• French Society of Human Genetics
• European Society for Medical Oncology
• European Oncology Nursing Society
• European Association for Cancer Research
• European Society of Human Genetics
• European Genetics Foundation
• European Cytogeneticist Association
• European Society of Gene Therapy
• Clinical Molecular Genetics Society

 USA Societies:

• American Cancer Society
• Haematology/Oncology Pharmacy Association 
• American Association for Cancer Research
• Association of International Cancer Research
• International Agency for Research on Cancer
• American Society of Human Genetics
• National Society of Genetic Counsellors
• American College of Medical Genetics
• American Board of Genetic Counselling
• American Board of Medical Genetics
• Nation Coalition for Health Education in Genetics
• International Society of Nurses in Genetics
• Association of Genetic Technologists
• Genetic Society of America

 Asia and Middle East Societies:

• Australian Epigenetics Alliance
• Asian Clinical Oncology Society
• Asian Oncology Nursing Society
• Asian Society of Gynecologic Oncology 
• Asian Society for Neuro-Oncology
• East Asian Union of Human Genetics Societies
• Association of Chinese Geneticists in America
• Hong Kong Society of Medical Genetics
• Japan Society of Human Genetics
• Genetics Society of Korea
• Korean Society of Human Genetics
• Genetics Society of Vietnam
• Turkish Association of Medical Genetics
• Japan Society of Gene Therapy
• American Human Geneticists of Indian Subcontinent Origin
• Stem Cell Society of India

List of Epigenetics and Human Disease Universities in Spain:

• University of Navarra
• University of Barcelona
• Autonomous University of Madrid 
• Zaragoza's University
• Pompeu Fabra University
• University of Alcalá

List of Epigenetics and Human Diseases Hospitals in Spain:

• Centre Cardiovascular Sant Jordi Hospital
• Hospital of Centro Medico De Asturias
• Hospital Puerta del Mar
• Hospital Universitario Reina Sofia
• Hospital Virgen De La Victoria
• Pius Hospital de Valls- Valls

Human Diseases 2023

The 6th International Conference on Epigenetics and Human Diseases was held in Valencia, Spain on June 8–9, 2023, and its theme was "Revolution in Human Disease." For a better world, we need diagnostic and therapeutic approaches.We would like to express our gratitude on behalf of the organising committee for the continuous support, active participation, keynote speakers, and moderators who helped make the Human Diseases 2023 conference a success.

Researchers, scientists, professors, engineers, students, and smart innovators from many nations actively took part in the conference and discussed the key developments and problems in artificial neural networks. Every participant gave the event excellent evaluations and reported having a wonderful time.  The opening ceremony and keynote speaker kicked off Human Diseases 2023, and we were blown away by everyone's presence and kind words.

To honour our keynote speakers and distinguished guests for their significant contributions to the success of this prestigious event, we would like to use this opportunity.

Finally, we would like to express our gratitude to all of the delegate specialists, company representatives, and notable individuals who supported the Conference by creating lively discussion forums. We would like to express our sincere appreciation to all of the participants, including the Editorial Board Members of our Open Access Journals, the Keynote Speakers, the Honourable Guests, the Valuable Speakers, the Students, the Delegates, and especially the Media Partners for their support in publicising this event.

With the unique feedbacks from the Conference Human Diseases 2023, we would like to announce the commencement of the 6th International Conference on Epigenetics and Human Diseases Conference which is going to be held during June 08-09, 2023 at Valencia, Spain.

Let us meet again @ Human Diseases 2023