Epigenetics and Human DiseasesConference

Noncoding RNA

Non-coding RNAs (ncRNAs) play a role in transcriptional and post-transcriptional regulation of gene expression. Some ncRNAs appear to play a role in epigenetic regulation. They're involved in heterochromatin formation, histone modification, DNA methylation targeting, and gene silencing, according to the findings.

A non-coding RNA (ncRNA) is a functional RNA molecule that is transcribed from DNA but not translated into proteins. Epigenetic related ncRNAs include miRNA, siRNA, piRNA and lncRNA. In general, ncRNAs function to regulate gene expression at the transcriptional and post-transcriptional level. Abundant and functionally important types of non-coding RNAs include transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well as small RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, exRNAs, scaRNAs and the long ncRNAs such as Xist and HOTAIR